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Updated: 9/11/21

Players in Sunday and Monday games will not be listed as doubtful or questionable by the league until Friday. When the traditional Out, Doubtful, Questionable, designations are released, we will have them here.
 Injury Report - Week 1
Pos Player Team Injury Status
LB Dennis Gardeck ARI Knee, Hand Out
WR Antoine Wesley ARI Illness Out
DT Star Lotulelei BUF Calf Out
WR Emmanuel Sanders BUF Foot Questionable
WR Shi Smith CAR Shoulder Out
S Tashaun Gipson CHI Back Questionable
LB Khalil Mack CHI Groin Questionable
LB Robert Quinn CHI Back Questionable
S Deon Bush CHI Shoulder Questionable
DT Eddie Goldman CHI Knee, Ankle Doubtful
WR Darnell Mooney CHI Back Questionable
LB Joel Iyiegbuniwe CHI Shoulder Questionable
LS Patrick Scales CHI Ankle Questionable
S Eddie Jackson CHI Wrist Questionable
CB Trae Waynes CIN Hamstring Out
K Chase McLaughlin CLE right Hamstring Questionable
T Michael Dunn CLE Back Out
WR Odell Beckham Jr. CLE Knee Questionable
LB Tony Fields II CLE Illness Out
DE Jadeveon Clowney CLE Illness Questionable
S Grant Delpit CLE Hamstring Questionable
S Ronnie Harrison CLE Ankle Questionable
C JC Tretter CLE Knee Questionable
LB Bradley Chubb DEN Ankle Questionable
DE Michael Brockers DET Shoulder Questionable
DT Levi Onwuzurike DET Hip Questionable
CB AJ Parker DET Shoulder Questionable
T Taylor Decker DET Finger Out
DE Nick Williams DET Elbow Questionable
DT Tyler Lancaster GB Back Questionable
LB Za'Darius Smith GB Back Questionable
S Vernon Scott GB Hamstring Out
CB Lonnie Johnson HOU Thigh Out
LB Kevin Pierre-Louis HOU Thigh Questionable
DE Jonathan Greenard HOU Illness Questionable
QB Deshaun Watson HOU Not injury related Out
G Quenton Nelson IND Foot, Back Questionable
G Danny Pinter IND Foot Questionable
CB Xavier Rhodes IND Calf Out
DE Kemoko Turay IND Groin Out
T Eric Fisher IND Achilles Out
CB Tre Herndon JAX Knee Out
DE Jordan Smith JAX Knee Questionable
CB Tyson Campbell JAX Calf Questionable
C Austin Blythe KC Abdomen Out
DE Frank Clark KC Hamstring Questionable
DT Derrick Nnadi KC Hip Questionable
S Trey Marshall LAC Ankle Out
RB Austin Ekeler LAC Hamstring Questionable
WR Ben Skowronek LAR Forearm Doubtful
WR Preston Williams MIA Foot Questionable
LB Anthony Barr MIN Knee Out
T Christian Darrisaw MIN Groin Out
WR Malcolm Perry NE Foot Out
T Yodny Cajuste NE Hamstring Questionable
WR Nelson Agholor NE Ankle Questionable
S Jalen Mills NE Ankle Questionable
LB Ronnie Perkins NE Shoulder Questionable
WR Tre'Quan Smith NO Hamstring Out
CB Ken Crawley NO Hamstring Out
T James Hurst NO Knee Questionable
RB Saquon Barkley NYG Knee Questionable
CB Adoree' Jackson NYG Ankle Questionable
TE Evan Engram NYG Calf Out
WR Keelan Cole NYJ Knee Questionable
S Sharrod Neasman NYJ Hamstring Out
RB La'Mical Perine NYJ Foot Questionable
G Landon Dickerson PHI Knee Out
LB Davion Taylor PHI Calf Questionable
S Rodney McLeod PHI Knee Out
LB Alex Highsmith PIT Groin Questionable
WR Jalen Hurd SF Knee Out
CB Emmanuel Moseley SF Knee Doubtful
DT Kevin Givens SF Hip Questionable
DT Javon Kinlaw SF Knee Doubtful
S Jordan Whitehead TB Hamstring Out
K Sam Ficken TEN right Groin Questionable
TE Tommy Hudson TEN Toe Questionable
CB Chris Jackson TEN Hamstring Questionable
WR Josh Reynolds TEN Foot Questionable
LB David Long TEN Hamstring Out