 Isaac Guerendo avoids major injury
MCL and ankle sprains
By: Doug Orth | Mon Jan 6, 11:30 pm
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RB Isaac Guerendo’s MRI this morning showed an MCL sprain and ankle sprain, source said. No ACL damage. (The Athletic - Matt Barrows)
FFToday's Take: Guerendo entered Week 18 with foot and hamstring issues. He failed to make it through the first drive in Week 18, ultimately leaving the game for good after two carries. The fourth-rounder's rookie season ends with 84 carries for 420 yards and four touchdowns and 15 catches for 152 yards. Guerendo will likely begin the 2025 season as the No. 3 back again behind Christian McCaffrey and impending restricted free agent Jordan Mason, but he showed enough this season to move ahead of Mason with a strong training camp.
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Isaac Guerendo unlikely to play in Week 16
Hamstring injury
By: Mike Krueger | Thu Dec 19, 12:05 pm
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After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the 49ers will be without RB Isaac Guerendo for Sunday’s game vs. Miami. Guerendo is dealing with a hamstring injury and is unlikely to play, per source. (Adam Schefter on X)
FFToday's Take: The 49ers suffer yet another injury at the running back position. Patrick Taylor is next up on the depth chart and should get the bulk of work against the Dolphins. Ke’Shawn Vaughn and Israel Abanikanda are also on the roster but haven't been with the team for very long. Taylor is an acceptable Flex option in Week 16.
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CMC, Jordan Mason land on injured reserve
49ers top two backs likely out for the season
By: Doug Orth | Mon Dec 2, 8:00 pm
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Kyle Shanahan said that Christian McCaffrey did injure his PCL and it is a 6-week recovery. His season now looks like it’s over.
49ers RB Jordan Mason suffered an ankle injury and also is being placed on injured reserve. (ESPN - Adam Schefter)
FFToday's Take: The news on McCaffrey was somewhat expected given how he fell on his final carry in Week 13. The news on Mason was a shocker since it was assumed he was pulled late due to the uncompetitive nature of the game. This leaves Isaac Guerendo as the next man up for the 49ers. While fantasy managers are certain to go head over heels for the rookie on waivers this week, it is important to note it has been a couple of months since a San Francisco running back has topped 20 PPR points. Guerendo should be considered a regular fantasy starter moving forward, but it might be a bit much to place the potential "league-winner" title on him - especially if LT Trent Williams (ankle) continues to miss time.
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Season-ending knee injury feared for Christian McCaffrey
PCL injury
By: Mike Krueger | Sun Dec 1, 11:34 pm
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49ers RB Christian McCaffrey suffered a potentially season-ending PCL injury, Kyle Shanahan announced in the team's postgame presser. (ESPN)
FFToday's Take: It's been a rough season on the injury front for McCaffrey and the 49ers as a team. We'll have to wait for more news, but the expectation is that this will put an end to McCaffrey's season. If so, expect San Francisco to move forward with Jordan Mason and Isaac Guerendo at running back. Mason will be a weekly RB2 and should be owned in every league.
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Christian McCaffrey expected to play Week 10
limited in practice
By: Mike Krueger | Thu Nov 7, 6:34 pm
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"He's been awesome these last 2 days. Hopefully that continues to go well. I expect to get him out there." - Kyle Shanahan on Christian McCaffrey's status for Sunday (Via Tolbert & Copes) (KNBR on X)
FFToday's Take: McCaffrey has been listed as limited in practice the last two days but it sounds like he's trending towards paying against Tampa Bay in Week 10. How much work he will get is still in question but if he's on the field, fantasy owners should get him in their lineup. Jordan Mason (shoulder) was limited in practice on Thursday as was Deebo Samuel (ribs).
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