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 Deebo Samuel expected to miss multiple games
Suffered a calf strain in Week 2
By: Doug Orth | Mon Sep 16, 11:30 pm
|  | More: 49ers WR Deebo Samuel strained his calf Sunday and is expected to miss a couple weeks, per HC Kyle Shanahan. (ESPN - Adam Schefter)
FFToday's Take: A "couple weeks" suggests that Samuel is dealing with a Grade 1 strain, since a Grade 2 strain usually means an athlete will be sidelined for at least a month. San Francisco will almost certainly rely more heavily on George Kittle and Brandon Aiyuk in the passing game now without Samuel around. Jauan Jennings will start in Samuel's place and could be worth starting in deeper leagues. Considering how often Samuel was seeing work out of the backfield, look for rookie Isaac Guerendo to spell Jordan Mason.
| Christian McCaffrey headed to IR, out next four games
Calf tightness, Achilles tendinitis
By: Mike Krueger | Sat Sep 14, 1:15 pm
| | ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and Achilles tendinitis. McCaffrey now will miss the next four games, at least, before the team assesses whether he can return in mid-October. (Adam Schefter on X)
FFToday's Take: We got word yesterday this may happen and now it has. McCaffrey was the overwhelming No.1 pick in fantasy football this season after the team projected this pre-season that McCaffrey to be fine for Week 1. That wasn't the case. Jordan Mason is looking more and more like a league winner with each passing day. Deebo Samuel Samuel should take on more of the rushing workload in the short-term until the team becomes more comfortable with rookie Isaac Guerendo who missed a good chunk of camp with an injury of his own.
| Christian McCaffrey Inactive for Week 1
Jordan Mason expected to start
By: Mike Krueger | Mon Sep 9, 6:54 pm
| | Christian McCaffrey is Inactive. With no McCaffrey, Jordan Mason will start the game with Patrick Taylor Jr. and rookie Isaac Guerendo also active and available. Guerendo likely will return kicks. (Matt Barrows on X)
FFToday's Take: McCaffrey was listed as Questionable with a calf injury that bothered him during training camp. He was limited in practice this week but was confident he would play. Mason becomes a viable RB2 as he gets the start. No word yet, if McCaffrey's calf issue will cause him to miss multiple games.
| Christian McCaffrey sidelined with calf strain
Unlikely to play in pre-season games
By: Mike Krueger | Tue Aug 6, 3:18 pm
| | #49ers RB Christian McCaffrey has a calf strain. He is unlikely to participate in this preseason, per Kyle Shanahan.
He's likely to miss a couple of weeks of practice, also. (Nick Wagoner on X)
FFToday's Take: We may not see much of McCaffrey the rest of the pre-season as the consensus No.1 pick in fantasy football has picked up a calf strain in camp. Matt Breida has been added to the roster as a result. The team has also been missing rookie Isaac Guerendo and Elijah Mitchell who both have hamstring issues.
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