| 1st Quarter |
| SF FG | 19 yards by David Akers. 7:25 Time Remaining. (6 plays, 79 yards. Time of Drive: 3:17). |
| 2nd Quarter |
| BUF FG | 31 yards by Rian Lindell. 10:46 Time Remaining. (12 plays, 75 yards. Time of Drive: 5:44). |
| SF TD | 43 yard pass from Alex Smith to Kyle Williams. (David Akers extra point is good). 9:54 Time Remaining. (2 plays, 74 yards. Time of Drive: 0:52). |
| SF TD | 28 yard pass from Alex Smith to Michael Crabtree. (David Akers extra point is good). 0:24 Time Remaining. (1 plays, 28 yards. Time of Drive: 0:05). |
| 3rd Quarter |
| SF TD | 1 yard run by Frank Gore. (David Akers extra point is good). 9:06 Time Remaining. (5 plays, 66 yards. Time of Drive: 2:44). |
| 4th Quarter |
| SF TD | 10 yard pass from Alex Smith to Mario Manningham. (David Akers extra point is good). 14:12 Time Remaining. (13 plays, 94 yards. Time of Drive: 7:48). |
| SF TD | 16 yard run by Colin Kaepernick. (David Akers extra point is good). 9:55 Time Remaining. (7 plays, 67 yards. Time of Drive: 3:05). |
| SF TD | 3 yard run by Anthony Dixon. (David Akers extra point is good). 1:11 Time Remaining. (11 plays, 69 yards. Time of Drive: 6:29). |
