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Depth Charts are organized by Fantasy & Team. This is to help you determine when a non-starter, injured, or suspended player has more Fantasy value than a player listed above him on the official Team depth chart.

 Offense 5/17/22 
Fantasy Team  Player  Player Note
QB1QB1 Trey Lance 
QB2QB2 Nate Sudfeld 
QB3QB3 Brock Purdy Rookie
QB4QB4 Jimmy Garoppolo 12/26/21: Thumb
RB1RB1 Elijah Mitchell 
RB2RB2 Jeff Wilson 5/25/21: Knee
RB3RB3 Trey Sermon 9/19/21: Concussion
RB4RB4 JaMycal Hasty 9/19/21: Sprained ankle
RB5RB5 Tyrion Davis-Price Rookie
RB6FB1 Kyle Juszczyk 
WR1WR1 Deebo Samuel 11/28/21: Groin; 10/31/21: Calf
WR2WR2 Brandon Aiyuk 
WR3WR3 Jauan Jennings 
WR4WR4 Ray-Ray McCloud 
WR5WR5 Danny Gray Rookie
WR6WR6 Malik Turner 
WR7WR7 Marcus Johnson 
WR8WR8 Austin Mack 
WRWR KeeSean Johnson 
TE1TE1 George Kittle 10/3/21: Calf
TE2TE2 Ross Dwelley 
TE3TE3 Charlie Woerner 
TE4TE4 Tanner Hudson 
TE5TE5 Troy Fumagalli 
K1K1 Robbie Gould 10/4/21: Groin
K2K2 Mitch Wishnowsky 

Note:

 Defense 5/17/22 
Fantasy Team  Player  Player Note
DL1DE1 Nick Bosa 
DL2DE2 Arik Armstead 
DL3DT1 Javon Kinlaw 10/29/21: ACL
DL4DT2 Hassan Ridgeway 
DL5DE3 Kemoko Turay 
DL6DT3 Maurice Hurst 
DL7DE4 Kerry Hyder 
DL8DT4 Kevin Givens 
DLDE Charles Omenihu 
DLDT Kalia Davis Rookie
DLDE Jordan Willis 6/17/21: 6-game suspension
DLDE Dee Ford 
LB1LB1 Fred Warner 
LB2LB2 Dre Greenlaw 
LB3LB3 Samson Ebukam 
LB4LB4 Azeez Al-Shaair 
LB5LB5 Oren Burks 
LB6LB6 Drake Jackson Rookie
LB7LB7 Demetrius Flannigan-Fowles 
LB8LB8 Curtis Robinson 
DB1S1 Jimmie Ward 
DB2S2 George Odum 
DB3CB1 Charvarius Ward 
DB4CB2 Emmanuel Moseley 
DB5CB3 Ambry Thomas 
DB6S3 Talanoa Hufanga 
DB7CB4 Dontae Johnson 
DB8S4 Tarvarius Moore 6/8/21: Achilles
DBCB Jason Verrett 
DBCB Samuel Womack Rookie
DBCB Tariq Castro-Fields Rookie
DBCB Deommodore Lenoir 
DBCB Darqueze Dennard 
DBCB Ka'dar Hollman 

Related Link: San Francisco 49ers DEF/ST Team Page