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Depth Charts are organized by Fantasy & Team. This is to help you determine when a non-starter, injured, or suspended player has more Fantasy value than a player listed above him on the official Team depth chart.

 Offense 10/26/21 
Fantasy Team  Player  Player Note
QB1QB1 Jimmy Garoppolo 
QB2QB2 Trey Lance Rookie
RB1RB1 Elijah Mitchell Rookie
RB2RB2 JaMycal Hasty 9/19/21: Sprained ankle
RB3RB3 Trey Sermon 9/19/21: Concussion
RB4FB1 Kyle Juszczyk 
RB5RB4 Jeff Wilson 5/25/21: Knee - PUP list
RB6RB5 Trenton Cannon 
RB7RB6 Jacques Patrick 
RB8RB7 Raheem Mostert 9/12/21: Knee
WR1WR1 Deebo Samuel 
WR2WR2 Brandon Aiyuk 
WR3WR3 Trent Sherfield 
WR4WR4 Mohamed Sanu 
WR5WR5 Jauan Jennings 
WR6WR6 Jalen Hurd 8/20/20: ACL
WR7WR7 Richie James 8/27/21: Knee - out 6 weeks
TE1TE2 Ross Dwelley 
TE2TE3 Charlie Woerner 
TE3TE1 George Kittle 10/3/21: Calf
K1K2 Joey Slye 
K2K1 Robbie Gould 10/4/21: Groin
K3K3 Mitch Wishnowsky 

Note:

 Defense 10/26/21 
Fantasy Team  Player  Player Note
DL1DE1 Nick Bosa 
DL2DE2 Arik Armstead 
DL3DT1 Javon Kinlaw 
DL4DT2 D.J. Jones 
DL5DT3 Kevin Givens 
DL6DT4 Kentavius Street 
DL7DE3 Dee Ford 
DL8DT5 Maurice Hurst 9/2/21: - IR
DLDT Zach Kerr 
DLDE Arden Key 
DLDE Jordan Willis 6/17/21: 6-game suspension
LB1LB1 Fred Warner 
LB2LB2 Samson Ebukam 
LB3LB4 Azeez Al-Shaair 
LB4LB5 Demetrius Flannigan-Fowles 
LB5LB3 Dre Greenlaw 9/16/21: Core muscle - IR
LB6LB6 Mychal Kendricks 
DB1S1 Jimmie Ward 
DB2S2 Jaquiski Tartt 
DB3CB2 Emmanuel Moseley 
DB4CB3 K'Waun Williams 
DB5S3 Marcell Harris 
DB6CB4 Ambry Thomas Rookie
DB7CB5 Deommodore Lenoir Rookie
DB8S4 Talanoa Hufanga Rookie
DBS Tavon Wilson 
DBCB Davontae Harris 9/2/21: - IR
DBCB Dontae Johnson 
DBCB Josh Norman 
DBS Tarvarius Moore 6/8/21: Achilles
DBCB Dre Kirkpatrick 
DBCB Buster Skrine 
DBCB Jason Verrett 9/12/21: ACL

Related Link: San Francisco 49ers DEF/ST Team Page