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Najee Harris, PIT: 374 touches as a rookie.
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Javonte Williams, DEN: Should be lead back beginning in 2022.
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Christian McCaffrey, CAR: Injuries have limited McCaffrey to 10 games over the last two seasons.
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Austin Ekeler, LAC: PPR's RB3 in 2021 including 20 total TDs.
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Breece Hall, NYJ: Carter isn't going away but Hall should become lead back quickly.
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Nick Chubb, CLE: Four-straight seasons averaging over 5 yards per carry.
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Alvin Kamara, NO: Off-season arrest.
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Derrick Henry, TEN: Is the volume starting to catch up with Henry?
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Saquon Barkley, NYG: A change of scenery may do Barkley some good.
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Kenneth Walker, SEA: A good fit for a run-heavy team.
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Travis Etienne, JAC: Rookie year lost due to foot injury.
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Elijah Mitchell, SF: Worked his way into a lead back role.
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Cam Akers, LAR: Impressive recovery from Achilles injury in 2021.
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AJ Dillon, GB: Committee approach with Aaron Jones in 2022.
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J.K. Dobbins, BAL: Coming off ACL injury.
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Leonard Fournette, TB: Was third in receptions (69) among RBs in 2021.
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James Cook, BUF: Bills found their pass-catching RB after striking on out McKissic.
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Tony Pollard, DAL: Has the juice to vault into Tier 3 if opportunity presents itself.
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Josh Jacobs, LV: Fantasy's least favorite lead back increased his receiving work in 2021.
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Clyde Edwards-Helaire, KC: 10 games missed in two seasons.
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Damien Harris, NE: The TD machine is more valuable in Non-PPR leagues.
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Michael Carter, NYJ: Falls into a complementary role behind Hall.
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Rachaad White, TB: Isn't a threat to Fournette's role in 2022.
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Dameon Pierce, HOU: Opportunity for a quick ascent is there in Houston.
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Brian Robinson Jr., WAS: Power back likely to be Gibson's backup.
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Cordarrelle Patterson, ATL: Age isn't on C-Patt's side.
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James Robinson, JAC: Late-season Achilles injury is a concern.
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Isaiah Spiller, LAC: Chargers continue to look for a complement to Ekeler.
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Tyler Allgeier, ATL: Patterson is 31. Falcons need a young RB to elevate.
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Tyrion Davis-Price, SF: Could easily leapfrog Trey Sermon.
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Gus Edwards, BAL: Coming off ACL injury.
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Zamir White, LV: The Raiders declined the 5th-year option on Josh Jacobs.
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Raheem Mostert, MIA: Expected to be ready for 2022 following knee injury.
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Pierre Strong Jr., NE: Path to playing time is blocked by Harris and Stevenson.
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Hassan Haskins, TEN: Foreman gone to CAR. Titans looking for depth behind Henry.
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Tyler Badie, BAL: Recent signing of Mike Davis increases competition.
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Jerick McKinnon, KC: Was the best KC running back in their last four games.
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= Upside
= Risk
