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Favorites & Fades


Week 1

By: Nick Caron | HC Green | John Fessel | Rick Tittsler
Updated: 9/5/25

Thursday:

DAL @ PHI


Friday:

KC @ LAC


Sunday Early:

TB @ ATL | PIT @ NYJ | MIA @ IND | CAR @ JAX

NYG @ WAS | ARI @ NO | CIN @ CLE | LV @ NE


Sunday Late:

SF @ SEA | TEN @ DEN | DET @ GB | HOU @ LAR

BAL @ BUF


Monday:

MIN @ CHI

Notes:
- Fantasy Points Allowed data begins in Week 2
- Injury notes, Lines and Totals updated Sunday morning

Cowboys @ Eagles - (Caron)
Line: PHI -6.5
Total: 58.5



No Brainers:
WR CeeDee Lamb

Favorites: QB Dak Prescott

Cowboys quarterback Dak Prescott missed both games against the Eagles in 2024 due to injury, but he’s set to make his return to the lineup here in the NFL regular season opener on Thursday night. The Cowboys were held to just 13 total points in their two games against the Eagles in 2024, but Prescott was quite productive against this defense when he played against them in 2023. He threw for 645 yards and five touchdowns without an interception in those games and he was even productive in the one game he played against them back in 2022. Those numbers don’t exactly translate to the situation the Cowboys are in now, of course, but while their revamped offensive line is young and unproven, there’s hope to be had with the addition of wide receiver George Pickens this offseason.

With Micah Parsons sidelined, the Cowboys’ defense is in disarray, giving the Eagles a strong chance to put up points. That game script could push Dallas into a heavier passing attack than the coaching staff would normally like. There’s always some risk that Dak Prescott struggles with turnovers in this spot, but the upside of 40+ pass attempts makes him a solid QB1 play in Week 1.

On the Fence: WR George Pickens

While his time in Pittsburgh came to an end with some controversy, George Pickens has some serious potential now that he’s in a much higher-octane offense in Dallas. Pickens has the opportunity to play alongside multi-time Pro Bowl wide receiver CeeDee Lamb while catching passes from another multi-time Pro Bowl quarterback Dak Prescott.

Pickens is the type of big-bodied field-stretching wide receiver that the Cowboys have been missing in their offense. He immediately steps into a starting role out wide and should see a significant target share with the Cowboys only having Lamb as an established pass-catcher in the offense.

It may take some time before Pickens and Prescott create a connection, which is why he’s in the “On the Fence” category, but there’s some potential for a boom game here in his first game with his new team.

Fade: Cowboys Running Backs

Whether you’re reading information from the team beat writers, fantasy analysts, or the Cowboys’ staff themselves, you’ve probably heard a variety of opinions on the Dallas backfield. For Week 1, it appears that Javonte Williams will get the start and the bulk of the backfield touches, so he’s probably the best option if you’re absolutely in need and have to start one of them, but the most likely scenario here is that we’re going to see some sort of committee with Williams splitting snaps with fellow offseason acquisition Miles Sanders and rookie Jaydon Blue. We may even see return specialist KeVontae Turpin line up in the backfield for a few plays, which only further muddies the situation.

The Cowboys have the offensive firepower to put points on the board, but there’s a real chance that this game becomes a blowout, which would almost certainly lead to a pass-heavy game script and further limit this backfield.

There’s too much uncertainty and risk to trust any Dallas RB at the moment. This is a “stay away” situation until we get a better idea of what the coaching staff is thinking.

No Brainers: QB Jalen Hurts, RB Saquon Barkley, WR A.J. Brown

Favorites: WR DeVonta Smith

The defending Super Bowl champions are one of the strongest offensive plays on the board this week, and wide receiver Devonta Smith is no exception. Smith went off the last time the Eagles hosted the Cowboys, catching six of the seven passes for 120 yards and two scores.

While Smith doesn’t have the upside of A.J. Brown, he’s still a reliable WR2 with the potential for WR1 weeks. The biggest concern in this game is probably that the Eagles could get out to a hot start and end up relying on their running game rather than airing it out. Still, even if the Eagles are up by multiple scores, there’s a good chance that Smith was involved, which should allow him to provide enough fantasy production for managers to be happy at the end of the game.

On the Fence: TE Dallas Goedert

Dallas Goedert’s days of being a reliable TE1 for fantasy are probably in the past, but that doesn’t mean that he can’t still have useful games from time to time. Historically, Goedert has struggled to produce usable fantasy games when he’s been matched up against the Cowboys, but this game could be different. The Cowboys are now without superstar pass-rusher Micah Parsons, who left for Green Bay, leaving a huge hole on their defense. Like most tight ends, Goedert has often been asked to assist, or at least chip in pass protection when facing players like Parsons, so his pass-catching upside has been limited a bit in those contests. This will be the first time that Goedert has faced the Cowboys without Parsons since the pass-rusher was drafted, so look for Goedert to have more route-running opportunities than usual. Time will tell if that translates into better fantasy production, but it’s at least enough for him to be considered as a streaming option here in Week 1.

Fade: N/A

Get your Eagles into your lineup in what is expected to be one of the highest-scoring games of the week. This could even turn into a blowout in Philadelphia’s favor, which would give plenty of Eagles players a chance to get into the end zone.

Prediction: Eagles 28, Cowboys 20 ^ Top

Chiefs @ Chargers - (Fessel)
Line: KC -3.5
Total: 46.5

No Brainers: N/A

Favorites: QB Patrick Mahomes, WR Xavier Worthy, RB Isiah Pacheco

While Patrick Mahomes has been a bit of a fantasy football disappointment over the last couple of years, he's still physically in his prime and has finished 1st among QBs in fantasy points twice. And despite the aging of top target Travis Kelce, the offensive unit is looking up from where it’s been the last couple of seasons.

With Xavier Worthy entering his second year, Marquise Brown healthy and Rashee Rice due to return following finally being suspended, Mahomes has a lot to work with in which to get back to a Top 3-5 fantasy QB. Don't expect that right out of the gate, especially versus Jim Harbaugh and a respectable Chargers defense, but he's reasonably a QB1 against L.A.

Xavier Worthy finished as WR33 in fantasy points last season. He was tied with fellow rookie prospect Marvin Harrison Jr. for 39th among wide receivers in FPts/G (9.9). After the Chiefs lost Rice to injury in week 4, Worthy was up-and-down after being forced into a greater role. Between weeks 4 and 14, he had under 4 points on three occasions (including -1.6) and over 14 points twice. Then, in week 15, he took off, producing at least 16.6 fantasy points in five of his final six games (counting the post season). He saw his first two double-digit target games of his career during that time, and saw at least 6 targets in every game after Week 12.

Worthy also added 20 carries and 3 rushing touchdowns, offering some bonus traits reminiscent of early Tyreek Hill. Worthy can't be expected to take the kind of leap Hill did, but with Rice out for 6 games to start 2025, there's good reason to believe that Worthy will not just be the de facto WR1, but also a very productive one. The Chargers aren’t an easy matchup (16th fewest FPts/G to WR last year), but the benefits outweigh the risks, making Worthy a solid WR2 for Week 1.

After running back Isiah Pacheco returned from injury last season, he failed to regain his spot as the team's lead back, and only saw 13 carries in three post season games. Pacheco gets another crack at lead duties to being 2025, with 30-year-old Kareem Hunt and oft-injured Elijah Mitchell being his main competition in the backfield. A healthier Pacheco has a decent chance to win at least a 55/45 share of the workload.

He draws a Chargers defense that allowed over 200 yards rushing to opposing offenses twice down the stretch last season, and 168 to the Texans in a playoff loss. It's a winnable match up and arguably makes Pacheco a flex option for Week 1.

On the Fence: TE Travis Kelce

Aging tight end Travis Kelce enters 2025 trying to stop a steep slide that began in 2023, and saw him average just 8.5 yards per reception last season. He is clearly not the player he once was, and at 36 years old, a further decline is more likely than any significant bounce back.

Kelce is likely the 3rd option in the offense, largely looked to as a short-yardage and redzone target by Mahomes. A lot of redzone action could keep Kelce among the Top 6-8 tight ends, but with just 8 total touchdowns over the last two seasons, that is an uphill climb. Kelce should be at his healthiest - and most targeted (sans Rashee Rice) - early in the season, and carries back end TE1 value against the Chargers.

Fade: WR Marquise Brown

Hollywood Brown had 15 targets in two regular season games after returning from injury last year, but only saw 13 more targets in three post-season games. In the process, he did not top 46 yards receiving in any of last season's performances, nor did he score a touchdown. Brown has not been a fantasy football factor since the 1st half of 2023, when Arizona's Kyler Murray was regularly targeting him 10 or more times.

Since then, he’s been shackled by injury issues, but at least some of the upside is still there as the veteran receiver seems the healthiest he's been in some time. He'll likely be a useful asset for Mahomes, but with only one 1000-yard season in his career, it's far from a guarantee that Brown will be a reliable figure on a weekly basis. He's best to sit against a respectable Chargers pass defense that kept Mahomes under 250 passing yards in both meeting last season.

No Brainers: N/A

Favorites: WR Ladd McConkey

McConkey enters his sophomore season after having turned out an outstanding 10.3 yards per target on 112 targets as a rookie. He also put up 197 yards and a touchdown on 14 targets in a playoff loss to Houston. Ladd’s arrow is only pointing up for his career, though he will see increased target competition with rookie Tre Harris and veteran Keenan Allen in the mix.

Still, with how efficient McConkey was as a rookie, as well as the outright dominance he displayed at times as the season progressed, it’s hard to imagine him being anything less than Justin Herbert’s number 1 guy. Drawing a Chiefs defense that allowed the 9th most yards per drive last season and surrendered 5-67-1 to McConkey in his only matchup with them last season, he’s arguably a low end WR1 for opening week.

On the Fence: QB Justin Herbert, RB Omarion Hampton

Herbert finished just 18th among quarterbacks in fantasy points per game last season (17.0), even though his real-life numbers were solid — 23 touchdowns against only 3 interceptions. The Chargers added receiving help this offseason (rookie Tre Harris, veteran Keenan Allen), but the signing of Najee Harris and the first-round selection of Omarion Hampton signal that Greg Roman’s run-heavy philosophy will remain in place, which could cap Herbert’s fantasy ceiling.

On the defensive side, Kansas City wasn’t exactly a shutdown unit against quarterbacks, giving up the 12th-most fantasy points to the position in 2024. With no major defensive upgrades made, the matchup is reasonable, but volume concerns hold Herbert back from QB1 status. Consider him a high-end QB2 in Week 1.

Hampton enters his rookie season with plenty of buzz after being selected late in the first round of the 2025 NFL Draft. On the Chargers’ depth chart, though, he and Najee Harris are essentially co-starters — more RB1a and RB1b than clear-cut lead and backup. Harris continues to take criticism in fantasy circles, but he’s proven both durable (68 straight regular-season games played), tough to bring down (most broken tackles over the past four seasons), and reliable with the football (just five career fumbles). Simply put, Harris is still a trusted veteran who isn’t going to hand the job over easily.

Even with Harris missing some camp time due to a fireworks accident, the most likely scenario is a split backfield — and there’s a strong chance Harris gets the larger share of touches while Hampton adjusts to the pro game. The good news: the Chargers were top-five in rushing attempts last season, and Greg Roman’s scheme suggests more of the same in 2025. That volume should give Hampton enough opportunities to deliver flex value and possibly back-end RB2 production.

The bad news: Week 1 is a brutal draw. Kansas City allowed the fewest fantasy points to opposing running backs in 2024, and combining that with the uncertainty of Hampton’s workload makes him a risky flex play with upside rather than a reliable starter this week.

Fade: RB Najee Harris, WR Keenan Allen, WR Tre Harris

While it’s plausible that Najee Harris outpaces Omarion Hampton in touches early on, his role figures to be more specialized. Expect Harris to handle the bulk of the early-down, short-yardage, and goal-line work, but not see much involvement in the passing game. That role limits his week-to-week upside, making him more dependent on positive game scripts and soft defensive matchups. Unfortunately, he doesn’t get either in Week 1. Kansas City allowed just 3.8 yards per carry and nine rushing touchdowns all of last season, making Harris a tough sell. He’ll have flex-worthy spots down the line -- especially in what should be a more efficient offense than Pittsburgh’s -- but this week, he’s best left on the bench.

As for the passing game, the Chargers will lean heavily on the run under Greg Roman, especially in the early going. Even if negative game script forces more throws later, there isn’t enough clarity on where Harris or Allen fall in the target hierarchy to trust either in Week 1. Until roles solidify, both are better suited for benches outside of the deepest leagues.

Prediction: Chiefs 23, Chargers 21 ^ Top

Buccaneers @ Falcons - (Tittsler)
Line: TB -1.5
Total: 47.5



No Brainers:
RB Bucky Irving, WR Mike Evans

Favorites: QB Baker Mayfield, Emeka Egbuka

I could justify placing Mayfield with Irving and Evans in the section above. Don’t shy away from starting him this week. Last year, Baker posted 25.2 and 29.6 fantasy points in two games against the Falcons. He tossed 3 TDs in each of those games, but replicating his week-to-week passing-yardage variability, he finished with only 180 passing yards in the first but a healthy 330 in the second. On a team loaded with talent there’s a big range of outcomes, especially with a new play caller for Buccaneer Baker.

Rookie WR Emeka Egbuka is an opportunistic play in Week 1. The first-rounder has shown impressive skills in camp, and with both Chris Godwin and Jalen McMillan out for weeks it’s time to ride the E-Train. He’ll likely see some rushing and return opportunities this season, too. Need one more nudge to start him (especially in your daily lineups)? There is a long list of stud WRs coming out of Ohio State, including Cris Carter, David Boston, Terry Glenn, Michael Thomas, Marvin Harrison Jr, Garrett Wilson, Jaxon Smith-Njigba, Chris Olave and Terry McLaurin. Who has the Buckeyes record for most receptions? E² is your answer, with 205.

On the Fence: TE Cade Otton

While Otton will likely be undrafted in many 12-team leagues, his 2024 targets popped when Godwin or Evans missed significant time. With a new OC, opportunity shares among Otton, and RBs Irving and White (and Sean Tucker) are TBD. Weeks 1 and 5 present softer defensive matchups for Otton, with extra targets up for grabs, too.

Fade: WR Sterling Shepard

There’s no obvious reason to reach for Shepard this week, even with an abbreviated WR depth chart to start the season.

No Brainers: RB Bijan Robinson, WR Drake London

Favorites: TE Kyle Pitts

I never imagined writing those words together, before researching this piece. Aside from a solid rookie year, Pitts has disappointed. In fact, most games he has disappeared. He scored a touchdown in just three games last year, and three games the previous year. So how did he make my “favorites” this week? In his two games against the Bucs in 2024, Pitts posted 7/88/0 and 4/91/2. Those two efforts are his most productive fantasy games in 2-1/2 years! The one thing that concerns me, is the Falcons might need his blocking to help the 3rd-string right tackle. I’m not suggesting you sit a TE1 and kick-it with Kyle, but I am saying for DFS (or even a player prop), this is the week Pitts could be cherry.

On the Fence: WR Darnell Mooney (shoulder)

I like Mooney more than most, even though he’s not the first or second choice in the passing game (on a team that likes to run). His 15.5 YPC in 2024 is encouraging, as Penix can throw the deep ball. Last year’s numbers were a significant improvement over his last two years in Chicago, posting 106/64/992/5. But recent news has me “recalculating,” for last-minute drafts. On August 20th, the Falcons lost their starting right tackle, Kaleb McGary, for the season. It’s worse than you think. McGary has started since 2019, and his back-up is already out for 6-8 weeks. Right tackle is the blind-side for lefty QB Penix, who tends to hold the ball a bit longer than he should. Bijan’s job just got harder, overall scoring could fall a bit and WR routes just became shorter to reduce sacks.

Fade: QB Michael Penix Jr.

The Falcons saw something in Penix, and surprised the football world (especially starting QB Kirk Cousins) when they drafted him 8th-overall in the 2024 draft. The final three games of his rookie season, Penix paired 3 TDs with 3 INTs. The Falcons pass the football on just 53% of their plays, with stud RB Bijan Robinson leading the ground game. Penix can throw a strong ball downfield, and in time, that will help WRs Mooney and McCloud keep defenses honest. You’re unlikely to use Penix in Week 1, even in super-flex formats. He might be rolling left more frequently, since losing his top-2 right tackles. If Tampa Bay gets up early, Penix and the passing game could be tested the entire second half. He is likely as good at kicking field goals as he is rushing, so assume zero points on the ground.

Prediction: Buccaneers 27, Falcons 17 ^ Top

Steelers @ Jets - (Caron)
Line: PIT -2.5
Total: 37.5

No Brainers: N/A

Favorites: N/A

On the Fence: WR DK Metcalf, RB Jaylen Warren

DK Metcalf, now Pittsburgh’s WR1 after his trade from Seattle, brings explosive potential to the 2025 season. In 2024, he posted 1,114 yards and eight touchdowns on 66 receptions, commanding 37.9% of his team’s air yards with a 12.8-yard average depth of target. His size and speed make him a prime target for Aaron Rodgers, who now commands the Steelers’ offense. Rodgers has a history of heavily targeting his top receiver, as seen with Davante Adams in both Green Bay and most recently with the Jets this past season, which bodes well for Metcalf’s volume in Pittsburgh’s offense. However, Week 1 against the New York Jets is a challenging matchup.

The Jets’ defense, anchored by Sauce Gardner, ranks among the NFL’s best at limiting fantasy points to wide receivers, often shadowing top threats like Metcalf. While Rodgers’ precision could keep the game close, the Jets’ elite secondary is likely to restrict Metcalf’s big-play opportunities. Pittsburgh’s run-heavy scheme under Arthur Smith and Metcalf’s adjustment to a new team add further risk, making a breakout game less likely. While his WR1 upside makes him tough to bench, the matchup suggests caution. He’s a low-end WR2 for Week 1.

Running back Jaylen Warren who is no longer competing with Najee Harris for touches, now has a whole new battle with rookie backfield-mate Kaleb Johnson. Johnson doesn’t have quite the draft capital that Harris did so we should expect that Warren gets the bulk of the touches at least here in Week 1, making him a decent floor play who also has the potential for a boom game if he’s able to make a connection in the passing attack with Aaron Rodgers. Rodgers has historically targeted his running backs heavily in the passing game, so there’s some potential for a multi-catch game for Warren.

Fade: RB Kaleb Johnson

While rookie running back Kaleb Williams could be the long-term option in the Pittsburgh offense, history tells us that he’ll likely play a minimal role here in Week 1. Jaylen Warren has played well enough to earn himself the “start” as a veteran and his versatile skill set makes him difficult to pull off the field. Keep an eye on Johnson’s performance in the opportunities he’s given as it could give us a better indication of how he’s used in the future, but he’s a very risky option in Week 1.

No Brainers: N/A

Favorites: WR Garrett Wilson

Pittsburgh's secondary ranked among the NFL's toughest against WRs in 2024, containing both total receptions and big plays. They made things even more difficult on opposing QBs by adding Jalen Ramsey this offseason, who is expected to match up frequently against opposing WR1s like Garrett Wilson.

However, Fields' scrambling ability opens doors for screens and extended plays. If the offensive line withstands T.J. Watt and the run game gets going early, Wilson could exploit softer zones for chunk gains. While this is a difficult on-paper matchup, his outlook tilts positive thanks to being the only real focal point in the passing game, making him a strong floor play.

On the Fence: RB Breece Hall

Breece Hall enters Week 1 as the Jets' lead back in an offense designed to lean on the ground game and set up play-action while utilizing Hall’s elite pass-catching ability for screens and checkdowns. Healthy with no reported injuries, Hall is set for a solid workload but faces committee concerns -- Braelon Allen is expected to take increased short-yardage and goal-line carries, while Isaiah Davis may steal change-of-pace reps, potentially capping Hall’s ceiling. Fields’ mobility could open lanes on designed runs and create dump-off opportunities, boosting Hall’s floor in half-PPR formats despite a reduced carry share.

Pittsburgh’s run defense ranked among the NFL’s toughest in 2024, allowing just 98.7 rushing yards per game and the 10th-fewest fantasy points to RBs. Their stout front seven, led by T.J. Watt’s disruptive pressure, often forces mistakes while also limiting explosive plays. The Jets’ offensive line faces a tall order against this rebuilt Steelers front. If the line holds and the run game gains traction early, Hall could exploit gaps for some big gains. However, this tough matchup favors a reliable floor through receptions -- which Justin Fields has a history of feeding to his backs -- over a breakout rushing performance, making him a volume-dependent flex play with limited touchdown upside due to Braelon Allen’s role.

Fade: QB Justin Fields

Justin Fields takes the reins as the Jets' starting QB, leveraging his dual-threat ability to anchor a run-heavy offense designed to open play-action opportunities. Reunited with ex-Ohio State teammate Garrett Wilson and paired with lead back Breece Hall, Fields is poised for a high-volume role, both passing and rushing. Fields’ 2023 success with the Bears -- elevating D.J. Moore to career highs -- suggests potential to make Wilson a focal point, but the backfield committee of Hall, Braelon Allen, and Isaiah Davis may lead the team to limit designed QB runs to preserve Fields’ health. Still, Fields’ scrambling ability and screen-game usage should maintain a solid fantasy floor.

Pittsburgh’s defense was one of the NFL’s stingiest in 2024, allowing just 98.7 rushing yards per game and T.J. Watt’s relentless disruption caused plenty of issues for opposing QBs. Their secondary, bolstered by Jalen Ramsey, clamps down on quick passes, potentially forcing Fields into extended plays or checkdowns. The Jets’ compromised O-line, missing Alijah Vera-Tucker, faces a steep challenge against this front, which will likely limit deep shots. If the run game with Hall and Allen gains early traction, that could open things up for Fields to exploit play-action and bootlegs for chunk plays or rushing yards. However, this tough matchup -- in Fields’ first game as a Steeler -- leans toward a modest floor via scrambles and short passes, making him a risky QB1 play but a solid QB2.

Prediction: Steelers 20, Jets 17 ^ Top

Dolphins @ Colts - (Tittsler)
Line: IND -1.5
Total: 46.5



No Brainers:
RB De’Von Achane

Favorites: WR Jaylen Waddle, Dolphins D/ST

I’m not high on the Dolphins in 2025, and WR Tyreek Hill (age 31, wrist surgeries) sits atop my own do-not-draft list. Waddle (age 26, healthy) should exceed lowered expectations coming off a down year, assuming Tua can stay healthy. With one-season wonder, TE Jonnu Smith, now in Pittsburgh, his atypical 112 targets from 2024 are literally up for grabs. Tagovailoa will go out of his way in Week 1 to find Waddle, Achane and even newcomer WR Nick Westbrook-Ikhine, considering the ongoing feud he and his teammates/staff have with Hill.

I smell a slight upset in Indiana. The Fins should limit RB Jonathan Taylor, and win the turnover battle. The Colts are projected to win 7.5 games in 2025, and with Miami’s defense focused on Taylor, I’m not sure this is one of them. I’ll take a mediocre pass defense against Daniel Jones’ 70/47 career TD/INT ratio, especially considering he only got half of the snaps in camp.

On the Fence: QB Tua Tagovailoa, WR Tyreek Hill

Tua has been “effective” as a starter, and has averaged 21 fantasy points/game over the last three years. The obvious issue is his injury history, specifically concussions. You likely won’t need him in Week 1, but if you’re building a super-flex roster, you could do worse than Tagovailoa against the ineffective Colts. He is healthy and has offensive weapons. Tua also benefits from Achane turning a random 3-yard check down into an 18-yard gain.

It's completely understandable if you start the Cheetah against Indy. An elite athlete with speed is an early target of every fantasy GM, but “Tyreek 2025” feels different to me. Hill had off-season surgeries to repair his wrist, bad behaviors late in 2024 rubbed coaches and teammates the wrong way and last year he wasn’t nearly as productive as previous efforts. There have been trade rumors, too. It’s entirely possible the wrist injury, sustained in a joint practice with the Commanders during training camp last year, impacted his entire campaign. With his QB healthy, the ever-dangerous Achane demanding attention and the Dolphins passing on 57% of their plays, Tyreek could post top-14 WR numbers in Indianapolis. Don’t let my negative vibes put you off Hill.

Update: Waller had a setback Thursday and has been ruled Out.

Fade: TE Darren Waller (hip), RB Ollie Gordon II

Drafted in 2015, and making his first NFL appearance since the 2023 season (1 total TD), Waller comes out of retirement to start at tight end for the Dolphins. Is there a tight end shortage of which I’m not aware? Week 1 could have been much worse for Waller -- it could’ve been outside in Miami’s heat, instead of indoors, against weak TE coverage. But never underestimate GM/HC egos. They’ll likely force him 3-4 targets, since they don’t want a goose-egg at the position after letting Jonnu Smith, TE4 in 2024, run the seam all the way to Pittsburgh.

Ollie is a great “out-of-nowhere” story with some solid preseason moments against backups, but let’s not get carried away when building your first lineup of the season. This 21-year-old thumper, 6’2” and 225 pounds, could post a rushing stat line of 6/19/3 in some game this season. I’m not expecting it this week, although RB Jalen Wright is out a few weeks, following a medical procedure.

No Brainers: RB Jonathan Taylor

Favorites: TE Tyler Warren

Considered the top-TE in the draft class, the Colts we thrilled to land the John Mackey Award winner at 14th-overall. In his final season at Penn State, Warren (6’5”, 256 pounds) caught 104 passes for 1,233 yards. It gets so much better -- he had 8 touchdowns receiving, 4 rushing, and threw a TD pass! The Colts haven’t featured the tight end position in a few years, but that changes on Sunday, September 7th.

On the Fence: QB Daniel Jones, WR Josh Downs, WR Michael Pittman Jr.

QB Anthony Richardson never had a chance, once HC Shane Steichen said “consistency” would be the ultimate factor in the Colts QB competition. Just because Daniel Jones won that duel is no reason for him to represent your fantasy team in Week 1. Indianapolis will throw a bit this week because of RB Jonathan Taylor’s tough match-up, but sheer volume does not guarantee success. I see mostly short routes for Indianapolis receivers in this game, which could lead to a “whopper” for Warren.

Josh Downs strained his right hamstring in a joint practice with Green Bay, but appears to be ready. During September 2024, QB Jones connected on 2 of 14 (14.3%) passes beyond 20 yards. Not a good combination for this receiver -- don’t overreach.

Pittman can beat Miami’s DBs on 70% of his routes, but I’m skeptical about accurate mid/deep throws from Jones. Pittman’s back is much better, so I see a near-equal division of short receptions among active wide receivers.

Fade: WR Alec Pierce

Considering the Colts QBs, you likely didn’t target Pierce, except in Best Ball. He did have extended playing time and 7 TDs last season, following injuries to other receivers. But there’s no Week 1 roster management involved here, considering the lack of accuracy on Jones’ deep throws. Keep him on a watch list, in case the Indianapolis passing game begins to click in the coming weeks.

Prediction: Dolphins 24, Colts 22 ^ Top

Panthers @ Jaguars - (Tittsler)
Line: JAX -3.5
Total: 46.5

No Brainers: RB Chuba Hubbard

Favorites: WR Tetairoa McMillan

Tetairoa McMillan, drafted 8th-overall, amassed a 34% target share last season for the Arizona Wildcats. He had been learning alongside veteran Adam Thielen in camp, and has a 3-5” height advantage on Jaguars defenders. T-Mac will be targeted early and often, but faces coverage rolling in his direction. It’s not a stretch to forecast 7 catches in his debut, with Thielen (MIN) off the roster. His presence will boost the entire Carolina offense in 2025.

On the Fence: QB Bryce Young, WR Xavier Legette

Young has looked overwhelmed for much of his first two years. But toward the end of last season, he was finally in QB2 territory. You didn’t draft him to start in Week 1, but fantasy GMs are understandably excited about having the 6’4”, 219-pound McMillan in his huddle. This Jaguars defense will offer some exploitable match-ups, and I’m curious to see if Young can take advantage at all levels of the field.

Legette finished his disappointing rookie season 84/49/497/4, with 8 drops. The Panthers were so “impressed,” they drafted McMillan about an hour into the 2025 draft! I’m still trying to make sense of Legette’s 2.30 yards-after-catch. The dude stands 2.08 yards (6’3”) tall. Yes, sub-par pass placement factors in -- so does falling forward. But in late August he became Carolina’s defacto WR2, so he has moved up from “Fade” to “On the Fence” for Week 1. Trading away Thielen, might indicate Legette has shown the coaches something in his second camp. Jalen Coker landed on IR (4-games), so WR3 duties will fall to a rotation of David Moore, Jimmy Horn Jr. and re-signed Hunter Renfrow.

Fade: TE Ja’Tavion Sanders, TE Tommy Tremble

Sanders will likely start, with Tommy Tremble coming off the PUP list two weeks ago. TE Targets are unusual in Carolina, but with WR2 Adam Thielen unexpectedly in Minneapolis, Sanders could see a couple of short targets. The JAX-D has trouble covering TEs last season (10th-most FPts allowed), but stick with your starter.

No Brainers: WR Brian Thomas Jr.

Favorites: WR Travis Hunter

I’ll consider starting an amazing athlete against mediocre coverage, in a game with the o/u set at 46.5 points. If QB Trevor Lawrence sported a career-completion percentage higher than 63.3% (Justin Fields hit 65.8% in 2024), Hunter would be a “No Brainer.” In Week 1, I believe offensive-minded Liam Coen and the team who moved up to get Hunter in the draft, will give him every chance to hit 5/50/1.

On the Fence: QB Trevor Lawrence, RB Tank Bigsby, RB Travis Etienne, RB Bhayshul Tuten

I doubt many folks will start T-Law in Week 1, but he has a chance to exceed (low) expectations. The first thing HC Liam Coen will adjust is the depth of his throws. Shorter passes will bump his overall completion percentage, get the ball quickly to his playmakers and sustain drives. The addition of Hunter (4.40 in his draft-day forty), gives him another receiver who can turn a 6-yard cross into a 20-yard gain. Fellow-rookie Bhayshul Tuten can, too. His 40-yard dash, timed at 4.32 seconds, and 40.5” vertical jump each ranked 1st among 31 running backs at the combine.

You’ll need a three-sided coin to decide which Jaguars RB will get you the most points this week. Training camp did nothing to clarify their usage, and the fantasy-fallout provides the worst RBBC this side of Dallas. I’m in the minority, thinking Bigsby’s touchdown potential gives him an edge (over the course of the season). Many analysts are sticking with Etienne, as a capable RB with receiving skills. Others are enthusiastic about Tuten’s speed and upside. The good news is that Jacksonville RBs have the best Week-1 matchup in the NFL. The bad news is those points are going to be split 2-1/2 ways, and nobody can tell you with any certainty who gets the “half.”

Fade: TE Brenton Strange

Pulling a Dolphins-like TE reset, the Jags allowed Evan Engram to join the Broncos. Strange becomes the starter, after filling-in for Engram (hamstring, then shoulder surgery) during 2024. HC Coen doesn’t feature the TE position, but WR injuries would give Strange more opportunities, as they did for Cade Otton last season in Tampa Bay.

Prediction: Jaguars 27, Panthers 24 ^ Top

Giants @ Commanders - (Caron)
Line: WAS -5.5
Total: 45.5

No Brainers: WR Malik Nabers

Favorites: N/A

On the Fence: RB Tyrone Tracy Jr.

Typically, breakout running backs don’t find their names in fantasy football articles about why they’re bound to lose touches to a rookie mid-round running back the following year, but that’s exactly what we have this season with the Giants’ Tyrone Tracy. Week 1 will reveal the Giants’ trust in Tracy after his 1,100-total-yard 2024 season, but he’ll need to outshine Cam Skattebo and improve on his Week 9 performance against Washington last year, when he managed 66 yards on 16 carries with one catch and no touchdowns.

The Giants’ offensive line and quarterback play are poised to improve from 2024, boosting optimism for Tracy’s outlook. With Russell Wilson now leading the Giants’ offense, enhanced passing efficiency should create more opportunities for Tracy in both the receiving game and crucial red-zone carries. Despite some risk, Tracy offers a relatively safe floor with significant Week 1 volume compared to other backfield options league-wide, making him a solid RB2.

Fade: RB Cam Skattebo

While Cam Skattebo’s dynasty value or potential role a month from now could spark a different discussion, fantasy managers should temper expectations for the fourth-round rookie in Week 1, as he’s likely to see limited touches behind Tracy.

Skattebo missed much of training camp with an injury and is currently listed not only behind Tracy, but also Devin Singletary, on the Giants’ official depth chart. That alone doesn’t necessarily mean that Skattebo won’t be utilized here in Week 1, but it does mean that we can’t trust him in our fantasy lineups until we see a change in the situation.

No Brainers: QB Jayden Daniels

Favorites: WR Terry McLaurin

Aside from quarterback Jayden Daniels, Terry McLaurin might be the only piece in the Washington offense that we can have any sort of confidence in heading into Week 1. McLaurin has been long-established as the top passing game option in Washington and even with the offseason acquisition of Deebo Samuel, he is still in line to lead the team in every passing game statistic that matters for fantasy purposes.

While McLaurin did struggle against the Giants in the two games he played against them in 2024 (6-22-0, 2-19-2), he did manage to get into the end zone twice in Week 9 when they last played, so there’s no reason to press the panic button on him just based on the matchup.

On the Fence: RB Austin Ekeler

The Commanders’ backfield has been the talk of the fantasy world over the past few weeks since the team was rumored to be moving Brian Robinson Jr. -- and then they went ahead and did it. This immediately led to massive speculation that the team had elevated rookie Jacory Croskey-Merritt into the starting role. However, we’ve found out that not only is that not the case, but the backfield may be as crowded as three, four, or even five heads.

Jeremy McNichols, Chris Rodriguez Jr., Jacory Croskey-Merritt, and even Deebo Samuel could all see backfield snaps here in Week 1. But as expected, veteran Austin Ekeler leads the depth chart. He’s not projected to see a traditional “starter” level of carries, he should play the majority of passing downs and there’s plenty of reason to believe that he’ll lead the team in total snaps at the position, making him both the highest floor and highest ceiling option in the bunch.

This situation is disgustingly crowded and very difficult to predict so it’s probably best to avoid it entirely, but if you have to go with one then it should probably be Ekeler -- at least for now.

Fade: RB Jacory Croskey-Merritt

The player with the most exciting profile in the Washington backfield is definitely rookie Jacory Croskey-Merritt, but the problem is that he’s stuck at the bottom of the depth chart and will likely need to play himself into a bigger role as the season goes on. Veteran coaches like Dan Quinn tend to prefer veteran players who they’ve seen on the field under the bright lights and that doesn’t bode well for Croskey-Merritt in Week 1.

Don’t be surprised if “Bill” sees snaps on just a drive or two in this one. We just have to hope that he does something special with one of those touches that could justify him being given a bigger role heading into Week 2.

Prediction: Commanders 27, Giants 20 ^ Top

Cardinals @ Saints - (Tittsler)
Line: ARI -6.5
Total: 43.5

No Brainers: RB James Conner, TE Trey McBride

Favorites: QB Kyler Murray, WR Marvin Harrison Jr., K Chad Ryland

Murray has a wide range of outcomes but this game feels like a good spot with the Cardinals favored by 6.5 points. He’s rushing only 4-5 times each game, but he did post 572 yards with 5 TDs on the ground last season. The Saints’ defense doesn’t scare anyone, and QB Spencer Rattler gets the start, meaning Murray could see 70+ offensive plays in the Caesars Superdome, and should finish the week a top-14 QB. If he runs one in, he could be QB9 to start the year.

Mighty Marvin had a so-so rookie season, with 116/62/885/8 for 198.5 fantasy points (WR30). It wasn’t awful, but expectations for him were sky-high heading into last season. Fellow-rookies Ladd McConkey, Malik Nabors and Brian Thomas Jr separated themselves from Harrison by 40, 73 and 82 fantasy points, respectively. Among Saints defenders, only 5’11” Kool-Aid McKinstry has a shot to contain him (6’4”). The Cardinals will scheme Harrison open, and toward (notably) less-talented coverage. His forecast inside the dome calls for mid-double-digit fantasy points.

Chad Ryland doesn’t pop into your head as a K1, and I get that. Only a few of his cousins drafted him in fantasy. However, he could be a sneaky start, with a very-low ownership number. I sense most of this game being played on the Saints’ half of the field, and 12-14 (coveted) kicker points are a possibility.

On the Fence: N/A

Fade: WR Michael Wilson

Wilson has been stuck in WR5 territory his first two seasons in the league, averaging 556 yards and 3.5 TDs per and we’ve got no indication his role is changing. So, barring an in-game injury, don’t expect many opportunities for Wilson, Greg Dortch or Zay Jones.

No Brainers: N/A

Favorites: RB Alvin Kamara

Listed above, are all the players whose entire Week 1 success in isn’t directly tied to QB Spencer Rattler. Admit it, you’d have the same list for this game.

At the end of the 2024 season, Kamara finished ahead of expectations as RB9, due in large part to injuries at quarterback and wide receiver. Drafting him in 2024 paid dividends, with 950 rushing yards, 543 receiving and 8 total TDs. Enter new HC Kellen Moore, a new staff and sophomore QB Rattler as the starter (Derek Carr retired 2 weeks after the NFL draft). A top-20 season in a rebuilding year could prove challenging for the 30-year-old Kamara as the Saints are expected to win only 5-6 games. The fantasy community is generally expecting fewer carries/yards/TDs, but a slight uptick in receptions as (either) Saints quarterback looks for short completions. I see that playing out in Week 1. Against softer defenses, like Arizona, Kamara should match expectations. Tougher matchups will see 8 defenders and 16 eyes on AK until the QB situation and the new offensive system stabilize.

On the Fence: WR Chris Olave, WR Rashid Shaheed, TE Juwan Johnson

The Saints won only five games in 2024 -- Olave played eight games, Shaheed managed six. Hopefully 2025 features this talented duo for all 17, but matching that humble five-win total is certainly in play. I’m being generous keeping these WRs out of the “Fade” category, to start the Rattler/Shough show. Olave is a fluid, top-12 talent at the position with soft hands, and Shaheed’s game is all about the deep ball (17.5 yards per reception in 2024).

I see three things working in favor of these receivers in Week 1 and beyond: (1) Kellen Moore knows which (few) Saints are his playmakers, (2) the 2025 Saints will be playing from behind, almost as much as the Cleveland Browns and (3) defenses will be more concerned with Kamara, than Rattler’s passing game. Olave and Shaheed, when healthy, will hold up their end of the bargain.

Johnson is an underrated TE who delivers when his number is called. Finishing 2024 squarely in TE2 territory, JJs biggest limiting factor was playing alongside “TE” Taysom Hill for 8 games last season. Hill remains out for Week 1, and maybe all of 2025. Johnson will repeatedly find an opening 5-yards downfield, and could become Rattler’s second-best friend to start the season.

Fade: QB Spencer Rattler

Derek Carr missed seven games in 2024, so we got a preview of the Rattler. It wasn’t great. We currently have him ranked as QB35, meaning 3 non-starting QBs will likely beat his fantasy numbers by year’s end. Against the Cardinals, there will be several chances for success. That’s where the good news stops in Week 1. The likelihood of those opportunities coinciding with NFL-quality execution on his part will be the exception, not the rule. It will be a “decent” day if he tosses 200 yards and a touchdown, with only 1 interception. A success would be enabling Olave and Shaheed a combined 8 receptions, and Kamara and Johnson another 10. The reality could be closer to 180/1/2, with 3 sacks and 4 pre-snap penalties, learning his second system in as many seasons.

Prediction: Cardinals 26, Saints 13 ^ Top

Bengals @ Browns - (Green)
Line: CIN -5.5
Total: 48.5

No Brainers: QB Joe Burrow, RB Chase Brown, WR Ja’Marr Chase, WR Tee Higgins

Favorites: N/A

On the Fence: TE Mike Gesicki

Cincinnati is unique to an extent in fantasy terms because it’s truly an offense built around four players: an MVP caliber quarterback, a workhorse back, and two top-level receivers. In 2024, the trio of Brown, Chase, and Higgins accounted for 4,001 of the team’s 6,291 yards -- that’s almost 64%, and it could be more this year as Zack Moss was the lead back for the first month of last season. All of which is to say, when four players are such focal points offensively, there are limited chances for everyone else. Gesicki is probably the next-best bet. He finished third on the club in receiving last year (65-665-2) and was a bigger part of the offense as the season wore on, which included 18 catches in the final two games. The Bengals handed him a new three-year deal back in March, and he’s likely to be the No. 3 option in the passing game. He managed just three catches for 16 yards in two games with Cleveland last year, though, and feels like a stretch as a starting tight end this weekend.

Fade: WR Andrei Iosivas

Iosivas effectively took over for Tyler Boyd as WR3 for the Bengals last season, and the Princeton product had his moments, finishing the season with 479 yards and 6 TDs. He caught just 36 passes in 17 games, however, and his ability to contribute at even a marginal level for owners hinged on whether he reached the end zone in a given week or not. Iosivas could have some appeal throughout the year based on a variety of factors, but with all 32 teams in action and most players healthy to start the year this doesn’t look like one of those weeks.

No Brainers: WR Jerry Jeudy, TE David Njoku

Favorites: N/A

On the Fence: RB Jerome Ford

Cleveland’s backfield is a mess. Nick Chubb left in free agency. Quinshon Judkins, the team’s second-round pick, is the only player from the 2025 draft that remains unsigned, and it’s unclear when he’ll debut for the club. That leaves fourth-round pick Dylan Sampson and Ford, the team’s leading rusher last season. That sounds more impressive than it is as Ford registered a pedestrian 565 yards on the ground, and even when he was the “starter” last year, the Browns never gave him more than a dozen carries in a game. So, where does that leave Ford for Week 1? Well, he appears to be their best option, but that’s never convinced the team to give him a full-time load. As an RB3 or flex, Ford might deliver a decent return on investment.

Fade: QB Joe Flacco

This is a tough one. If we rewind to 2023, Flacco averaged 321 yards, 2.3 TDs, and 1.7 INTs per game during a six-start stretch for the Browns. Last year with the Colts, those numbers fell across the board to 252 yards, 1.7 TD, and 1 INT per outing. Flacco has Jeudy and Njoku, but beyond that this is a suspect group. We already touched on the running back room, and at receiver we’re looking at Cedric Tillman, who had one good three-game stretch in his career, and Jamari Thrash. While Flacco is capable of putting up decent numbers, he’s also capable of having mistakes snowball.

Prediction: Bengals 31, Browns 20 ^ Top

Raiders @ Patriots - (Caron)
Line: NE -2.5
Total: 43.5

No Brainers: TE Brock Bowers

Favorites: RB Ashton Jeanty

Ashton Jeanty enters Week 1 as the Las Vegas Raiders’ presumed lead running back, drafted sixth overall in 2025 to anchor a run-heavy offense under coach Pete Carroll and OC Chip Kelly. Jeanty’s explosive burst, vision, and pass-catching ability make him a three-down workhorse in a backfield where Zamir White and Dylan Laube are expected to see limited roles, with Raheem Mostert filling in on third downs. Jeanty’s pass protection has also earned the coaches’ trust, positioning him for a strong PPR floor.

The Patriots’ run defense ranked eighth-worst in PPR fantasy points allowed to RBs in 2024, conceding 24.6 points per game. Their front seven remains vulnerable to dynamic backs in space and Jeanty’s 7.0 college yards per carry could exploit their subpar run-stopping unit. If the Raiders’ O-line establishes early control and the game script favors the run, Jeanty could rack up some serious production in his NFL debut. Even with New England potentially stacking the box, this matchup favors a high PPR floor and ceiling, making him a must-start RB1 with minimal committee concerns.

On the Fence: WR Jakobi Meyers

Despite a trade request over a contract dispute, Jakobi Meyers enters Week 1 as the Las Vegas Raiders’ clear WR1, cemented by Amari Cooper’s surprise retirement on Thursday. With a thin receiving corps featuring just Tre Tucker along with rookies Dont’e Thornton Jr. and Jack Bech, Meyers is set for a high target share in a run-heavy offense led by QB Geno Smith under OC Chip Kelly.

The Patriots’ pass defense was average in 2024, ranking 21st in PPR fantasy points allowed to WRs, conceding 32.5 points per game, 2,494 receiving yards, and 204 receptions to WRs. They often allowed short completions, aligning perfectly with Meyers’ short-to-intermediate route-running strength. If New England focuses on stopping Jeanty’s ground game or TE Brock Bowers, Meyers could exploit soft zones as Smith’s safety valve. This matchup looks tailor-made for a high PPR floor with double-digit target upside, making Meyers a solid WR3/Flex in PPR formats.

Fade: WR Dont’e Thornton Jr., WR Tre Tucker, and WR Jack Bech

With Amari Cooper’s retirement, rookies Donte' Thornton and Jack Bech, along with Tre Tucker are in line to compete for scraps in a thin receiving corps alongside TE Brock Bowers and top WR Jakobi Meyers.

Thornton, a rookie with raw speed, struggles with route polish and drops. Bech, another rookie, is a possession receiver but lacks separation skills and is buried on the depth chart. Tucker, in his third year, offers deep-threat potential but is inconsistent, with only 47 receptions last season. The committee approach and limited passing volume cap their ceilings for now, at least until we see one of them break free from the others and establish themselves as the unquestioned third option in this passing game.

No Brainers: N/A

Favorites: QB Drake Maye

Drake Maye enters Week 1 poised for a breakout sophomore season under new coach Mike Vrabel and OC Josh McDaniels. His 2024 rookie campaign showcased his dual-threat ability 421-2 on the ground in 13 games). With Stefon Diggs, TreVeyon Henderson, and an upgraded O-line, Maye's supporting cast is much improved, boosting his ceiling. His rushing prowess ensures a solid floor and if he can even turn in league-average passing numbers then he'll almost certainly be a must-start at QB this season.

The Raiders’ pass defense was porous in 2024, ranking 20th in points allowed to QBs per, conceding 21.3 FPts per game. Their middling secondary struggles against dynamic QBs and their pass rush lacks consistency beyond Maxx Crosby.

If Maye gets the ball out quickly, he can exploit Las Vegas’ soft zones and target Diggs or Demario Douglas. This favorable matchup, combined with Maye’s mobility and McDaniels’ aggressive play-calling, makes him a great low-end QB1 streaming option with sneaky top-five upside this week.

On the Fence: WR Stefon Diggs

Transitioning to a new offense under OC Josh McDaniels, Stefon Diggs now finds himself attached to second-year QB Drake Maye after a 2024 season marred by a late-season knee injury. Now fully healthy with no reported concerns, Diggs’ elite route-running should cement him as the unquestioned top target in a receiving corps alongside Demario Douglas and a cast of other mediocre talents. His integration into a new system adds slight risk to his ceiling in his Patriots debut, but the Raiders’ pass defense was exploitable in 2024.

Their secondary struggles against precise route-runners like Diggs, especially in zone coverage, but Maxx Crosby’s pass rush could pressure Maye if the offensive line struggles. Diggs' upside is somewhere around 8-to-10 targets, but there's also a relatively low floor, making him a risky but startable option given his projected target share and health.

Fade: RB Rhamondre Stevenson, RB TreVeyon Henderson

The Patriots’ backfield enters Week 1 as a committee, with Rhamondre Stevenson and rookie TreVeyon Henderson splitting touches under OC Josh McDaniels who historically favors multi-player backfields. Stevenson (801-7, 168-1), the veteran, disappointed in 2024, leading to the Patriots drafting Henderson with a second-round pick. Henderson brings explosive speed and pass-catching ability but is expected to ease into a complementary role, potentially handling change-of-pace and receiving duties to start the season. With Antonio Gibson as a third option, the split projects roughly 55-40-5 (Stevenson-Henderson-Gibson), limiting both primary backs’ volume. This crowded backfield, paired with Maye’s own rushing, caps both players’ immediate fantasy ceilings.

Despite high hopes for Henderson’s explosiveness long-term, both should be benched in PPR formats unless you lack viable options, as the backfield split needs clarity.

Prediction: Patriots 23, Raiders 20 ^ Top

49ers @ Seahawks - (Fessel)
Line: SF -1.5
Total: 43.5

No Brainers: TE George Kittle

Update: Christian McCaffrey (calf) missed practice Friday and is Questionable.

Favorites: QB Brock Purdy, RB Christian McCaffrey (calf), WR Ricky Pearsall

Brock Purdy, a top-12 QB in his first two full seasons, is poised to continue that trend as long as McCaffrey is active and Jauan Jennings isn’t limited by his “calf injury.” Despite Seattle allowing the 9th-fewest fantasy points to QBs in 2024 (15.8 per game), Purdy posted two of their five 20+ point QB performances, averaging 21 points in his last three starts against them, making him a solid backend QB1.

Unlike a year ago, running back Christian McCaffrey is truly set to go for Week 1 of the season… or is he? He popped up on the injury report Thursday, limited with a calf injury living up to his reputation as the biggest wild card in all of fantasy football in 2025. He's a must start if he’s able to suit up, but follow his practice status on Friday and throughout the weekend.

After a delayed 2024 due to an armed robbery, Ricky Pearsall emerged late with 445 yards and 3 touchdowns over 11 starts, including an 8-141-1 line in Week 17 against the Lions. With Aiyuk out and Jennings recovering, Pearsall’s breakout potential is real against a Seahawks defense that allowed the 12th-most fantasy points to WRs (23.2 per game) in 2024, making him a flex play with WR2 upside.

On the Fence: N/A

Fade: WR Jauan Jennings (calf), RB Brian Robinson Jr.

After missing camp due to contract disputes and a calf injury, Jauan Jennings is set for Week 1 but seems disgruntled. He’s coming off a career-year that still fell short of 1,000 yards or 80 receptions but it was his best performance over four seasons. With limited offseason reps, it may be a bit much asking for a WR2 finish this week but that may change given McCaffrey’s availability. He’s currently a risky flex better suited for the bench.

Brian Robinson Jr. isn’t worth starting but should be monitored closely this weekend; if the 49ers limit McCaffrey’s workload due to his calf issue, Robinson could step into a prominent role in a potent offense. The Seahawks allowed 18.5 fantasy points to RBs (14th-most) in 2024.

No Brainers: WR Jaxson Smith-Njigba

Favorites: RB Kenneth Walker

In two games against the 49ers last season, Kenneth Walker averaged 44 yards rushing but caught 10 passes and scored in both, averaging 18 touches per game. Facing a 49ers defense that lost several front-seven members and allowed 4.7 yards per carry in 2024, Walker is a high-end RB2 with RB1 upside, especially in PPR formats given his receiving role.

On The Fence: WR Cooper Kupp

After seeing just 3 targets in each of his final three 2024 regular-season games and 8 in two postseason games, most analysts have written off Cooper Kupp, but at 32, his 2024 (100 targets, 700 yards, 6 TDs) mirrors Adam Thielen’s 2022 before a 1,000-yard rebound. Joining a Seattle offense led by Jaxon Smith-Njigba, Kupp faces a depleted 49ers defense (23.5 WR fantasy points allowed in 2024), making him a flex-level WR3 with upside if he regains form.

Fade: QB Sam Darnold

Sam Darnold, coming off a 6th-place fantasy QB finish in 2024 with the Vikings, signed a three-year deal with Seattle but now operates without Minnesota’s loaded offense or dome environment. The 49ers allowed 16.8 fantasy points to QBs (10th-fewest) in 2024, and despite their defensive losses, Darnold’s production is likely to fall between his Jets/Panthers struggles and last year’s highs, making him a mid-to-high-end QB2 this week.

Prediction: Seahawks 27, 49ers 24 ^ Top

Titans @ Broncos - (Fessel)
Line: DEN -8.5
Total: 42.5

No Brainers: N/A

Favorites: N/A

On the Fence: WR Calvin Ridley, RB Tony Pollard

Ridley is likely to see 8-10 targets weekly, now that first-overall selection Cam Ward is throwing him the football in 2025. That volume could start immediately, but what Ridley can do against elite cornerback Patrick Surtain II remains a question. His opportunity for heavy targets puts him in the flex conversation, but the likelihood of a pedestrian line (e.g., 4-5 catches for 50-60 yards, based on his 2024 average of 13.3 yards per catch) makes him a low-end WR3 this week.

Despite any coach speak to the contrary, Pollard is likely to see relatively high volume as Cam Ward gains experience, especially to keep Denver’s elite front-seven honest. Pollard, like Ridley, may struggle to produce efficiently against a Broncos defense that allowed the 7th-fewest fantasy points to RBs in 2024 (16.8 per game), but checkdowns and screens (Pollard had 44 catches last season) should be abundant, giving him fantasy relevance. He’s not exciting but remains a flex play as an RB3 in PPR formats.

Fade: QB Cam Ward

It looks to be a cruel end of summer for Cam Ward in Week 1. The rookie QB starts his NFL career against a stellar Denver defense that added linebacker Dre Greenlaw (quad) and cornerback Jaire Alexander in the offseason. This unit, which allowed the fewest points per drive (1.61) in 2024, has the potential to be one of the NFL’s all-time greats, and Ward will get a harsh introduction. With Denver’s top pass rush (39 sack differential), Ward should be holding a clipboard for your fantasy team on Sunday -- fade him outside superflex leagues.

No Brainers: N/A

Favorites: QB Bo Nix, WR Courtland Sutton, RB RJ Harvey

Bo Nix enters his second year with veteran safety valve TE Evan Engram joining an offense that badly needed another target option alongside Courtland Sutton. The Titans’ defense, while solid, gave up the 5th-most rushing yards and 3rd-most rushing touchdowns to quarterbacks in 2024, and Nix, who rushed for 430 yards and 4 touchdowns last season, is built to exploit this. The Broncos should control field position, and have ample red-zone opportunities, making Nix a QB1 this week.

Speaking of red-zone action, Courtland Sutton has raked in 18 touchdowns over the last two years, and his 6’4” frame makes him Denver’s best receiving option near the end zone. He may share targets with Engram in 2025, but the Titans’ secondary, which allowed the 10th-most fantasy points to WRs (24.2 per game) in 2024, is more favorable to Sutton than to the new tight end. Sutton is a strong WR2 this week.

The Titans gave up the 10th-most points to running backs last year, and despite defensive improvements, they’ll be tested by a Broncos team likely to let Tennessee’s rookie quarterback beat himself. This bodes well for rookie running back RJ Harvey, who, even if he doesn’t find success on the ground, is likely to contribute through the air as Nix checks down when Sutton and company aren’t open. Harvey may share time with J.K. Dobbins, but his high-end flex appeal with RB2 upside makes him a strong play.

On the Fence: TE Evan Engram

Tight end Evan Engram is a great fit with Bo Nix, as when healthy, he can dominate in the short-field area, averaging 4.6 receptions per game since 2018 (5.8 aDOT) with 114 catches in 2023 and 72% snap participation in most seasons. He has a good shot to finish inside the top-12 TEs, but the Titans tied for the 4th-fewest receptions allowed to the position in 2024 and added linebacker Cody Barton to bolster middle-field coverage. Engram is a borderline TE1 for Week 1, best for managers comfortable with a modest ceiling.

Fade: WR Marvin Mims

While Mims nearly doubled his fantasy output in 2024 with 110 points in 17 games and 6 touchdowns, his route-running remains limited, and some reps are reserved for returns. The Titans allowed 12 deep touchdowns last season, suiting Mims’ 14.2 average depth of target, but his low target share (under 15%) and competition with Sutton, Engram, and Franklin make him an unreliable WR4 in leagues without return-yardage scoring.

Prediction: Broncos 27, Titans 13 ^ Top

Lions @ Packers - (Green)
Line: GB -1.5
Total: 47.5

No Brainers: RB Jahmyr Gibbs, WR Amon-Ra St. Brown, TE Sam LaPorta

Favorites: N/A

On the Fence: RB David Montgomery

In 2023, Montgomery had 219 carries to 182 for Gibbs. Last year, that swung to 250 carries for Gibbs and 185 for Montgomery. Do we see a larger discrepancy in 2025? Time will tell. Montgomery did see a lot of work in two games against the Packers last season, logging 39 combined touches for 180 yards and a touchdown. On the road and with a defense that wants to unleash newly acquired Micah Parsons, it wouldn’t be a surprise to see the Lions try to control the game physically -- remember that Green Bay gave up their top interior DL, Kenny Clark, in that trade. Still, deploying Montgomery as more than an RB3 feels like a risk.

Fade: QB Jared Goff

Although the Lions have won three straight games in Green Bay, Goff’s output has been mediocre at best, averaging just 193 yards passing with 2 total TD passes across those three outings. As noted above, the Packers just made a move for Parsons to bolster their pass rush, but after he missed all of camp in a contract dispute with the Cowboys, they’ll likely need to pick their spots with the former All-Pro. Of course, the best way to neutralize Parsons to stay ahead of the chains, and that could mean a lot of running or short passes. We’re also about to see Goff without Ben Johnson for the first time in several years, which is another interesting subplot. Add it all up, and Goff seems like someone to avoid in the opener.

No Brainers: RB Josh Jacobs

Favorites: TE Tucker Kraft

In terms of talent, Kraft looks to be on the cusp of being viewed as a top tight end. That doesn’t always equate to fantasy value, though, and that’s where things get a little dicey (and it’s the reason he’s not a no-brainer). Despite a number of capable pass catchers, the Packers leaned on the run a lot in 2024, which meant limited opportunities for the wideouts and tight ends. To that end, Kraft saw more than five targets just four times last year. One of those came against the Lions, and he finished 2024 with seven catches (on 11 targets) for 75 yards and a score in two meetings. With some injury concerns at receiver, this could be a game where Kraft is heavily involved.

On the Fence: WR Matthew Golden

The first receiver taken in Round 1 by the Packers since Javon Walker in 2002, Golden drew loads of praise from the team’s beat writers. He reportedly looked like the team’s most talented wideout and, in particular, his hands stood out. There’s even been talk (and predictions) from those same writers about Golden winning the Offensive Rookie of the Year award, so the hype is out there. Now, it’s time to deliver. Golden and Romeo Doubs have been the only two consistently healthy wideouts among the team’s top five with Jayden Reed battling a foot injury and Christian Watson (knee) on the PUP. If you’re seeking an upside play from your WR3 slot, Golden is intriguing.

Fade: QB Jordan Love

While acknowledging that Love played basically the entire 2024 season compromised by a Week 1 knee injury, his numbers against the Lions were uninspiring. In two games (both losses), Love passed for 479 yards, 1 TD, and 1 INT -- of the five TDs the Packers scored against Detroit last year, four came on the ground. The team invested in bolstering the interior of their offensive line during the offseason, and we know Matt LaFleur likes to run the football. The Lions could also dust off some new looks defensively after replacing coordinator Aaron Glenn. It figures to be a bit of a chess match, and recent history portends a lot of Jacobs for Week 1.

Prediction: Packers 24, Lions 20 ^ Top

Texans @ Rams - (Fessel)
Line: LAR -3.5
Total: 43.5

No Brainers: WR Nico Collins

Favorites: RB Nick Chubb

Chubb looked sharp with his cuts and broke multiple tackles during his 2025 preseason, earning praise from head coach DeMeco Ryans. He’s got significant upside if he can be 90% of his pre-injury self, and could run away with the starting role while Joe Mixon is sidelined with a mysterious foot injury. He’ll face a Rams defense that allowed 4.7 yards per carry and 19.1 fantasy points to RBs (12th-most) in 2024 making Chubb is a strong flex play with potential for 15+ touches.

On the Fence: WR Jayden Higgins

Jayden Higgins is built for big plays and red-zone production but isn’t a lock for significant targets outside of downfield and end-zone looks when Christian Kirk (hamstring) is healthy. With Kirk missing this game, Higgins could see a boosted role (15-20% target share) against a Rams secondary that allowed 23.8 fantasy points to WRs in 2024, making him a flex-level WR3 option for Week 1.

Fade: QB C.J. Stroud

After a disappointing 2024 season (3,727 yards, 20 TDs) marred by offensive line struggles and injuries to Tank Dell and Stefon Diggs, Stroud faces a tough Week 1 test. New addition Jayden Higgins, alongside Nico Collins and Dalton Schultz, offer hope, but a revamped offensive line still adjusting and a well-coached Rams defense (allowed 18.2 QB fantasy points per game in 2024) make Stroud a fade -- sit him until the line and Higgins gel in regular-season action.

No Brainers: WR Puka Nacua, RB Kyren Williams

Favorites: WR Davante Adams

While the Texans have a strong defense, Derek Stingley Jr. can only cover one receiver, and with Puka Nacua drawing attention, Davante Adams should face less coverage than a player of his caliber typically sees. Now 32, Adams delivered 1,000+ yards in 2024 and has a competent quarterback in Matthew Stafford as long as his back holds up. With 103 career receiving touchdowns and the Rams’ potent offense, Adams is a WR2 until proven otherwise.

On The Fence: QB Matthew Stafford

Matthew Stafford finished 30th in fantasy points per game among quarterbacks with at least four games played in 2024, despite a 6.6 ANY/A, 94 passer rating, 7.3 yards per attempt, 8 interceptions, and 28 sacks. The Rams’ run-heavy approach (519 pass attempts over 15.5 games in 2023-2024) may shift with the Davante Adams’ addition, and against Houston’s stiff run defense (4.5 yards per carry allowed), a fresh Stafford could see increased attempts, making him a QB2 with QB1 upside despite no rushing production (41 yards, 0 TDs in 2024).

Fade: Blake Corum

While there have been some questions about drop offs in Kyren William’s statistical efficiency among the fantasy football community, there’s been no indications that the Rams are looking to create a committee, let alone look another direction in 2025. As it stands, especially against the Texans run defense, no other Rams back should be fired up at this time, even in deeper leagues.

Prediction: Rams 20, Texans 17 ^ Top

Ravens @ Bills - (Caron)
Line: BAL -1.5
Total: 50.5

No Brainers: QB Lamar Jackson, RB Derrick Henry

Favorites: TE Mark Andrews

Mark Andrews heads into Week 1 as the Baltimore Ravens’ sole top tight end, set to capitalize on a favorable role with Isaiah Likely (foot)) sidelined. Andrews himself is healthy after a 2024 season where he scored a career-high 11 TDs, and is Lamar Jackson’s go-to target, especially in the red zone.

His playoff performance against the Bills last year (5 catches, 61 yards, but a costly fumble and dropped two-point conversion) showed he can produce against them despite the miscues. With Likely out and Zay Flowers nursing a knee injury, Andrews should see increased snaps and targets in a potential shootout, boosting his PPR floor and ceiling.

The Bills’ pass defense was average in 2024, ranking 16th in PPR fantasy points allowed to TEs, conceding 12.0 points per game. Their secondary, despite adding depth, struggles against versatile tight ends like Andrews, who exploits seams and physically dominates in the end zone. This matchup makes Andrews a must-start TE1 in PPR formats.

On the Fence: WR Zay Flowers

Zay Flowers enters Week 1 as the Baltimore Ravens clear WR1. Coming off a 2024 season with 74 catches, 1,059 yards, and four TDs, Flowers is the primary target, especially with TE Isaiah Likely out (foot injury) and Mark Andrews drawing coverage. Rashod Bateman and rookie Devontez Walker are secondary options, ensuring Flowers sees eight-to-10 targets. His shifty route-running and YAC secure a reliable PPR floor, making him a low-upside, high-floor play and on the right side of the fence in Week 1.

Fade: WR DeAndre Hopkins

DeAndre Hopkins enters Week 1 as a depth receiver for the Ravens, following a 2024 season split between the Titans and Chiefs. At 33, he’s well past his prime and he's competing with at least two receivers ahead of him on the depth chart as well as Mark Andrews at tight end. With Isaiah Likely out, Hopkins may see a slight uptick in targets, but his diminished speed and contested-catch ability limit him to a low-upside PPR flex option, despite his name recognition.

No Brainers: QB Josh Allen, RB James Cook

Favorites: N/A

On the Fence: WR Khalil Shakir (ankle)

Khalil Shakir steps into Week 1 as a pivotal slot receiver for the Buffalo Bills, thriving in Josh Allen’s pass-heavy offense. His 2024 season included a strong showing versus Baltimore, with 10 catches for 129 yards across two games (including playoffs). While rookie Keon Coleman may have higher long-term upside, Shakir’s high catch rate and short-area quickness secure a reliable PPR floor. He does, however, lack the high-score potential to become a real difference-maker most weeks.

Fade: TE Dalton Kincaid

Dalton Kincaid serves a key pass-catching role for the Bills, but he certainly struggled to live up to expectations a year ago. Kincaid was one of the biggest disappointments in fantasy football and while he's still young, it's worth noting that he struggled against Baltimore, managing just six catches for 58 yards across two games (including playoffs).

Competing with Khalil Shakir and rookie Keon Coleman for targets in a crowded offense, isn’t great for his fantasy outlook, and he's also limited by a minimal red-zone role. This dynamic makes him a fade in PPR formats, lacking the upside for a confident start until we see him get back to the kind of player we saw in his rookie season.

Prediction: Ravens 28, Bills 27 ^ Top

Vikings @ Bears - (Green)
Line: MIN -1.5
Total: 43.5

No Brainers: RB Aaron Jones, WR Justin Jefferson, TE T.J. Hockenson

Favorites: RB Jordan Mason

Last season went about as well as it could have possibly gone for Jones, who appeared in every game for just the third time in eight seasons and wound up setting career highs in carries (255) and rushing yards (1,138). The veteran is entering his age-31 season, though, and the team clearly wants to lighten his load, which is why they traded for Mason after getting little from Cam Akers in 2024. Mason led the 49ers in rushing last year, racking up 789 yards on 153 carries (5.2 YPC) in 12 games. Look for him to push into more of a timeshare role with Jones this year, which is something that the Packers did with the latter throughout his seven seasons in Green Bay. Don’t be afraid to use the new arrival as a flex/RB3 this Monday night.

On the Fence: WR Adam Theilen

Back with the Vikings after a two-year stint in Carolina, Thielen is well past his prime. He was limited to 10 games last season due to injury, and at this stage of his career he’s little more than a reliable possession receiver. That doesn’t mean the 35-year-old can’t contribute, especially early on while the team tries to weather Jordan Addison’s three-game suspension. He should function as a security blanket of sorts for first-time starting QB J.J. McCarthy, and that might be especially valuable Monday night as the Bears did a nice job of defending Jefferson last year, meaning the Vikings could be looking for someone to step up. While not a safe selection, Thielen has a shot at low-end No. 3 value, particularly in point-per-reception formats.

Fade: QB J.J. McCarthy

No matter how good you look in practice or the preseason, you can’t simulate full-speed NFL football. The Bears will have had weeks to draw up a game plan for the first-time starter, and there’s no way of knowing just how much head coach Kevin O’Connell will keep the training wheels on McCarthy, whose first career start will come on the road against a divisional opponent in prime time. No pressure. Could McCarthy hit the ground running and put up big numbers? Sure, the Bears aren’t an elite defense. Is it worth risking him in your lineup? Probably not.

No Brainers: WR D.J. Moore

Favorites: WR Rome Odunze

Inconsistent as a rookie, Odunze drew praise throughout the preseason for elevating his game and displaying a burgeoning chemistry with Caleb Williams. It’s led to speculation that the second-year wideout might be ready to become the true go-to receiver in the passing game ahead of Moore. We might start to get a read on that situation against the Vikings, but even last year he got a lot of opportunities against Minnesota, being targeted 17 times in their two meetings. While there’s still room for pessimism with Odunze and the Bears offense, there’s plenty of reasons for optimism as well, so if you feel like rolling the dice on a high-upside option in Week 1, Odunze fits the bill.

On the Fence: QB Caleb Williams

Even the most ardent Bears supporter would have a hard time classifying Williams’ debut season as anything other than a mixed bag. The then-rookie held onto the ball too long and took too many sacks, and though he avoided the big mistakes (only six INTs) he lagged behind QBs drafted after him like Jayden Daniels and Bo Nix. The hiring of Ben Johnson as head coach was due in no small measure to the team’s desire to develop Williams. Will it work? We’re about to start finding out. Williams played well in two losses to the Vikings last year, posting 531 yards and 3 TDs, but Minnesota is a tough opponent with a creative defensive play caller.

Fade: TE Colston Loveland

Drafted 10th overall back in April, Loveland has leapfrogged steady but unspectacular Cole Kmet to take over as the starting tight end. It’s easy to see the vision and proclaim that Loveland will step in and deliver as a rookie the same way Sam LaPorta did for Johnson in Detroit when he posted an 86-889-10 line. Let’s calm down. LaPorta didn’t have a backup the caliber of Kmet in Motown, and Jared Goff had seven seasons under his belt, including one with Johnson calling the plays. Loveland absolutely offers TE1 upside this year. It just could be more prudent to wait for him to deliver before inserting him into your starting lineup.

Prediction: Vikings 20, Bears 16 ^ Top